Colonial Medical Supply
Telephone: 603-823-9911
Toll-free: 888-446-8427
Fax: 603-823-8799
cms@colmedsupply.com
TonoLab TonometerIntroducing the First Tonometer for the Research field
Please contact our office to request studies or references for the TonoLab or TonoVet -
How it works
Tonovet® for animalsThe tonometer is intended for use by general veterinary practitioners, veterinary ophthalmologists and other veterinary medical personnel. The device is a useful tool for measuring intraocular pressure on animal patients, as it is painless and therefore creates no anxiety.
The tonometer is based on a new measuring principle, in which a very light probe is used to make momentary contact with the cornea. The measurement is barely noticed by the animal and often does not even cause corneal reflex.
| Tonolab | |
|---|---|
| TLP-2007 | Box of replacement probes, 50 count |
| TLB | Replacement probe base |
| Tonovet | |
| TLP-2007 | Box of replacement probes, 100 count |
| TLB | Replacement probe base |
PanOptic™ OphthalmoscopeThe revolutionary PanOptic provides easy entry into the eye, together with a wider field of view to more easily observe conditions such as hypertension, diabetic retinopathy, and papilledema.
Binocular Indirect OphthalmoscopeOne of the most advanced BIO available, with state-of-the-art, convenient features plus lightweight, comfortable fit and increased stability.
IOP Measurement
PROBLEM:
Measuring Intraocular pressure in rats and mice
Large research efforts have been made in trying to beat glaucoma, a major cause of blindness in the western hemisphere. Early research, which was based on animal studies, suffered due to a lack of methodology to measure small eyes, such as those of rats and mice.
The basic research for glaucoma increased when it became possible to measure intraocular pressure (IOP) in the rate eye using the TonoPen. Using a mouse as a model for studies of glaucoma is more preferable because there are many more molecular/biological methods available. It is easier and more economical to maintain mice than larger animals.
Mice have similar eye physiology when compared to human eyes. However, the front chamber of a mouse eye contains only 2-4ul aqueous, making it a challenge to measure IOP, First measurements were made in 1997 by cannulating the eye of an anesthetized mouse with a very small needle. This method requires very deep anesthesia which in turn lowers the IOP. Cannulating the eye also damages it and causes infections.
SOLUTION:
A rebound tonometer
A rebound tonometer device for mouse IOP measurement was adapted from prototypes of those originally developed for human IOP measurements. The developed prototype was more accurate than the TonoPen in measuring the IOP of rats. In addition, the goal of measuring IOP from the mouse eye was successful and the prototype was able to measure IOP accurately in vitro and in vivo.
The method is based on impacting a very light probe to the eye at the very low speed (11-13mg, 0.1-0.2m/s)and measuring the motion parameters of the probe during collision to the eye (deceleration, impact time, etc,). The movement energy of the probe is very small (less than 0.25uJ) and most of that is rebounded (not absorbed by the eye) so there is no damage to the eye. Several measurements can be made over a long period of time. It is possible to measure with very light anesthesia so the IOP is not affected. Now Tiolat Oy (Helsinki, Finland) has launched a commercial version of the rebound tonometer "TonoLab" which has been adapted to read rat and mice IOP measurements. The TonoLab, offered by Colonial Medical Supply (Franconia, NH) has several advantages.